Characterization of novel bovine papillomavirus type 12 (BPV-12) causing epithelial papilloma.
Arch Virol
; 157(1): 85-91, 2012 Jan.
Article
em En
| MEDLINE
| ID: mdl-22033594
ABSTRACT
Bovine papillomavirus type 12 (BPV-12, putative type BAA1) was detected in epithelial papilloma located on the tongue of an infected cow. Then, the whole genome was sequenced, and phylogenetic analysis illustrated that it should be classified as a member of the genus Xipapillomavirus. The viral genome is 7197 base pairs in length and contains five early ORFs (E1, E2, E4, E7 and E8), three late ORFs (L1, L2 and L3), and a long control region that possesses replication regulatory elements. Meanwhile, mRNA of each gene was detected in the papilloma sample. The papilloma was identified as epithelial papilloma by histological and immunohistochemical examination. Based on the genome information and pathological properties, BAA1 was designated as BPV-12 in this study.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Papiloma
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Neoplasias da Língua
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Doenças dos Bovinos
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Infecções por Papillomavirus
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Xipapillomavirus
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article