Elimination of Borrelia burgdorferi and Anaplasma phagocytophilum in rodent reservoirs and Ixodes scapularis ticks using a doxycycline hyclate-laden bait.
Am J Trop Med Hyg
; 85(6): 1114-20, 2011 Dec.
Article
em En
| MEDLINE
| ID: mdl-22144454
ABSTRACT
A field trial was conducted in a Lyme disease-endemic area of New Jersey to determine the efficacy of a doxycyline hyclate rodent bait to prophylactically protect and cure small-mammal reservoirs and reduce infection rates in questing Ixodes scapularis ticks for Borrelia burgdorferi and Anaplasma phagocytophilum. The doxycycline-laden bait was formulated at a concentration of 500 mg/kg and delivered during the immature tick feeding season in rodent-targeted bait boxes. The percentage of infected small mammals recovered from treated areas after 2 years of treatment was reduced by 86.9% for B. burgdorferi and 74% for A. phagocytophilum. Infection rates in questing nymphal ticks for both B. burgdorferi and A. phagocytophilum were reduced by 94.3% and 92%, respectively. Results from this study indicate that doxycycline-impregnated bait is an effective means of reducing infection rates for B. burgdorferi and A. phagocytophilum in both rodent reservoirs and questing I. scapularis ticks.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vetores Aracnídeos
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Roedores
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Reservatórios de Doenças
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Doença de Lyme
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Ehrlichiose
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Doxiciclina
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Ixodes
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Borrelia burgdorferi
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Anaplasma phagocytophilum
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Antibacterianos
Idioma:
En
Ano de publicação:
2011
Tipo de documento:
Article