Multiplicity of infection does not accelerate infectivity evolution of viral parasites in laboratory microcosms.
J Evol Biol
; 25(2): 409-15, 2012 Feb.
Article
em En
| MEDLINE
| ID: mdl-22168551
Coinfection with multiple parasite genotypes [multiplicity of infection (MOI)] creates within-host competition and opportunities for parasite recombination and is therefore predicted to be important for both parasite and host evolution. We tested for a difference in the infectivity of viral parasites (lytic phage Φ2) and resistance of their bacterial hosts (Pseudomonas fluorescens SBW25) under both high and low MOI during coevolution in laboratory microcosms. Results show that MOI has no effect on infectivity and resistance evolution during coevolution over â¼80 generations of host growth, and this is true when the experiment is initiated with wild-type viruses and hosts, or with viruses and hosts that have already been coevolving for â¼330 generations. This suggests that MOI does not have a net effect of accelerating parasite adaptation to hosts through recombination, or slowing adaptation to hosts through between-parasite conflict in this system.
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Base de dados:
MEDLINE
Assunto principal:
Pseudomonas fluorescens
/
Fagos de Pseudomonas
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article