[Management of colorectal liver metastases after induction treatment. The pathologist's role in 2011]. / Prise en charge des métastases hépatiques d'origine colorectale après traitement d'induction. Place du pathologiste en 2011.
Ann Pathol
; 31(6): 427-32, 2011 Dec.
Article
em Fr
| MEDLINE
| ID: mdl-22172115
ABSTRACT
The management of colorectal liver metastases has been improved these last years. The efficacy of chemotherapy regimens and targeted therapies has led to a better prognosis. It has also allowed the resection of metastases initially unresectable. In this setting, the pathologist plays a major role. He is involved in the gross examination, in order to perform an adequate sampling of the lesions. He is also involved at the morphological level, for the assessment of the pathological response, which is now recognized as a prognostic factor and a marker of sensitivity or resistance to a given treatment. Moreover, the determination of predictive markers of response or resistance to induction treatments will constitute a supplementary and major challenge for the pathologist.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Patologia Clínica
/
Papel do Médico
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Neoplasias Colorretais
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Adenocarcinoma
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Quimioterapia de Indução
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Neoplasias Hepáticas
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Antineoplásicos
Idioma:
Fr
Ano de publicação:
2011
Tipo de documento:
Article