Improved skin test for differential diagnosis of bovine tuberculosis by the addition of Rv3020c-derived peptides.
Clin Vaccine Immunol
; 19(4): 620-2, 2012 Apr.
Article
em En
| MEDLINE
| ID: mdl-22301696
ABSTRACT
A peptide cocktail derived from the mycobacterial antigens ESAT-6, CFP-10, and Rv3615c allowed differentiation between Mycobacterium bovis-infected and M. bovis bacillus Calmette-Guérin (BCG)-vaccinated cattle when used as a skin test reagent for a "DIVA" test (i.e., a test capable of differentiating infected and uninfected vaccinated animals). Addition of the antigen Rv3020c improves the diagnostic sensitivity without compromising specificity in the face of BCG or Johne's disease vaccination.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tuberculose Bovina
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Medicina Veterinária
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Mycobacterium bovis
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Antígenos de Bactérias
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article