Escherichia coli with extended-spectrum ß-lactamase and plasmid-mediated quinolone resistance genes in great cormorants and mallards in Central Europe.
J Antimicrob Chemother
; 67(5): 1103-7, 2012 May.
Article
em En
| MEDLINE
| ID: mdl-22323500
ABSTRACT
OBJECTIVES:
Faecal Escherichia coli strains were isolated from great cormorants (Phalacrocorax carbo) and mallards (Anas platyrhynchos), which are commonly occurring waterbirds in Europe, and studied for resistance to cephalosporins and fluoroquinolones.METHODS:
Cloacal swabs or faeces from great cormorants and mallards in Central Europe were cultivated to isolate Escherichia coli strains with extended-spectrum ß-lactamase (ESBL) and plasmid-mediated quinolone resistance (PMQR) genes.RESULTS:
Ten ESBL-producing E. coli with the bla(CTX-M-15) or bla(CTX-M-27) gene were isolated from eight great cormorants (1.6%, n = 499). The bla(CTX-M) genes were harboured by plasmids of F and I1 incompatibility groups. CTX-M-27-producing isolates were identified as the epidemiologically important B2-O25b-ST131 clone. No ESBL-producing E. coli was isolated from 305 mallards. Eight E. coli isolates with PMQR genes [six aac(6')-Ib-cr and two qnrS1] were detected in six great cormorants (1.2%). Seventeen strains with qnrS1 were detected in 17 mallards (6%). The PMQR genes were located on plasmids of incompatibility groups F, N or X2. ESBL and PMQR genes were found on conjugative plasmids, enabling the horizontal spread of resistance.CONCLUSIONS:
Both great cormorants and mallards can spread epidemiologically important antimicrobial-resistant E. coli isolates to water bodies throughout Europe.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Plasmídeos
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Beta-Lactamases
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Cloaca
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Quinolonas
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Farmacorresistência Bacteriana
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Escherichia coli
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Fezes
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article