[Adult prostate sarcoma: a clinicopathologic study of 15 cases].
Zhonghua Bing Li Xue Za Zhi
; 40(11): 749-53, 2011 Nov.
Article
em Zh
| MEDLINE
| ID: mdl-22336158
ABSTRACT
OBJECTIVE:
To clarify the clinical and morphological features of adult prostate sarcoma (APS) and to further improve the knowledge and diagnostic accuracy for APS.METHODS:
Fifteen cases of APS were observed and analyzed on the clinical symptom, pathological features, treatment and prognosis.RESULTS:
Age of onset ranged from 22 to 77 years (mean 46.3 years). The majority of cases were presented with dysuresia. By digital rectal examination and imaging of the prostate, APS was often identified as a large tumor mass. There were 6 cases of leiomyosarcomas, 6 embryonal rhabdomyosarcomas, and 3 fibrosarcomas in this series. Follow-up data were available for 12 cases 7 cases died of the disease between 9 days and 360 days after surgery. Among 5 survived patients, 3 cases had recurrence after 2 to 24 months follow-up.CONCLUSIONS:
APS is a rare tumor that typically has clinical features earlier age of onset, fast-appeared urinary tract symptoms, significant mass effects, and poor outcome. Level of prostate specific antigen (PSA) is usually normal or lower. Final diagnosis relies on the features of histology and immunohistochemistry expression profile.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Sarcoma
/
Vimentina
/
Actinas
Idioma:
Zh
Ano de publicação:
2011
Tipo de documento:
Article