Roadmap for annotating transposable elements in eukaryote genomes.
Methods Mol Biol
; 859: 53-68, 2012.
Article
em En
| MEDLINE
| ID: mdl-22367865
ABSTRACT
Current high-throughput techniques have made it feasible to sequence even the genomes of non-model organisms. However, the annotation process now represents a bottleneck to genome analysis, especially when dealing with transposable elements (TE). Combined approaches, using both de novo and knowledge-based methods to detect TEs, are likely to produce reasonably comprehensive and sensitive results. This chapter provides a roadmap for researchers involved in genome projects to address this issue. At each step of the TE annotation process, from the identification of TE families to the annotation of TE copies, we outline the tools and good practices to be used.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Elementos de DNA Transponíveis
/
Genoma
/
Análise de Sequência de DNA
/
Eucariotos
/
Anotação de Sequência Molecular
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article