The effect of left ventricular (LV) remodeling on ventricular arrhythmia in cardiac resynchronization therapy (CRT-D) patients (antiarrhythmic effect of CRT).
Pacing Clin Electrophysiol
; 35(5): 592-7, 2012 May.
Article
em En
| MEDLINE
| ID: mdl-22429264
ABSTRACT
BACKGROUND:
In patients with low ejection fraction and ventricular dyssynchrony, cardiac resynchronization therapy (CRT) is an accepted therapeutic modality. In these patients, CRT can improve the quality of life and exercise tolerance in addition to improved survival. On the other hand, antiarrhythmic effects of CRT is a place of debate.METHOD:
In this study, we evaluated the effect of CRT-induced reverse remodeling on ventricular arrhythmia in heart failure patients. Patients with CRT were divided to two groups of responders and nonresponders. Responders were those with reduction of LVESD of more than 10% or increase in LVEF of more than 5%. They were visited and device analysis was performed during the follow-up.RESULTS:
One hundred and nineteen patients were enrolled in this study. Those with reverse remodeling experienced fewer ventricular arrhythmias after two years of follow-up (N = 2 vs 11, P = 0.001).CONCLUSION:
Reverse remodeling associated with CRT implantation can result in decreased frequency of ventricular arrhythmias.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Taquicardia Ventricular
/
Disfunção Ventricular Esquerda
/
Remodelação Ventricular
/
Terapia de Ressincronização Cardíaca
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article