Total synthesis of (-)-goniotrionin.
J Org Chem
; 77(8): 4046-62, 2012 Apr 20.
Article
em En
| MEDLINE
| ID: mdl-22443275
A stereoselective total synthesis of the reported structure of goniotrionin (4) has been accomplished. The key steps involved the opening of a chiral epoxide, a highly diastereoselective Mukaiyama aerobic oxidative cyclization, a selective 1,2-syn Mukaiyama aldol reaction, and a Noyori reduction.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Compostos de Epóxi
/
Furanos
/
Lactonas
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article