Relationship between brachial-ankle pulse wave velocity and cardiovascular risk factors: a multi-ethnic study.
Intern Med
; 51(6): 537-43, 2012.
Article
em En
| MEDLINE
| ID: mdl-22449659
ABSTRACT
OBJECTIVE:
The objective of the present multi-ethnic study was to explore whether an association exists between brachial-ankle pulse wave velocity (baPWV) and cardiovascular risk factors in China.METHODS:
Two hundred sixty-four adult subjects (152 subjects were of Han nationality, 70 subjects were from Uygur, 19 subjects were from Kazakh, 15 subjects were from Hui, and 8 subjects were of other nationalities.) aged 30-82 years were enrolled in the present study. The subjects' anthropometric, baPWV and laboratory measurements were recorded.RESULTS:
Age (p=0.000), systolic blood pressure (p=0.000), diastolic blood pressure (p=0.002), fasting blood glucose (p=0.000), and hemoglobin (p=0.019) differed significantly among the subjects in the baPWV quartile. Spearman correlation analyses indicated that baPWV was significantly and positively associated with age (r=0.584, p=0.000), systolic blood pressure (r=0.396, p=0.000), diastolic blood pressure (r=0.217, p=0.000), and fasting blood glucose (r=0.231, p=0.000). baPWV was significantly and negatively associated with erythrocyte number (r=-0.181, p=0.003) and hemoglobin (r=-0.192, p=0.002) levels. Multiple regression analyses suggested that age (ß=0.573, p=0.000), systolic blood pressure (ß=0.181, p=0.003), triglycerides (ß=0.160, p=0.008), and cholesterol (ß=0.132, p=0.020) were independently associated with baPWV.CONCLUSION:
Age, SBP, triglycerides, and cholesterol levels are independently and positively associated with baPWV.
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Base de dados:
MEDLINE
Assunto principal:
Doenças Cardiovasculares
/
Etnicidade
/
Índice Tornozelo-Braço
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article