Cardiomyocyte specific deficiency of serine palmitoyltransferase subunit 2 reduces ceramide but leads to cardiac dysfunction.

Lee, Su-Yeon; Kim, Jung Ran; Hu, Yunying; Khan, Raffay; Kim, Su-Jung; Bharadwaj, Kalyani G; Davidson, Mercy M; Choi, Cheol-Soo; Shin, Kyong-Oh; Lee, Yong-Moon; Park, Woo-Jin; Park, In-Sun; Jiang, Xian-Cheng; Goldberg, Ira J; Park, Tae-Sik

Lee, Su-Yeon; Kim, Jung Ran; Hu, Yunying; Khan, Raffay; Kim, Su-Jung; Bharadwaj, Kalyani G; Davidson, Mercy M; Choi, Cheol-Soo; Shin, Kyong-Oh; Lee, Yong-Moon; Park, Woo-Jin; Park, In-Sun; Jiang, Xian-Cheng; Goldberg, Ira J; Park, Tae-Sik.

Afiliação

Lee SY; Department of Life Science, Gachon University, Seongnam-Si, Gyeonggi-Do, Republic of Korea.

J Biol Chem ; 287(22): 18429-39, 2012 May 25.

Article em En | MEDLINE | ID: mdl-22493506

Assuntos

Ceramidas/metabolismo; Coração/fisiopatologia; Miocárdio/enzimologia; Serina C-Palmitoiltransferase/metabolismo; Animais; Glicemia/metabolismo; Western Blotting; Células Cultivadas; Marcação In Situ das Extremidades Cortadas; Lipídeos/sangue; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Serina C-Palmitoiltransferase/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ceramidas / Serina C-Palmitoiltransferase / Coração / Miocárdio Idioma: En Ano de publicação: 2012 Tipo de documento: Article

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