Clinical trials in gastric cancer and the future.
J Surg Oncol
; 107(3): 289-97, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-22514058
ABSTRACT
Following the first successful gastric resection for gastric cancer by Theodor Billroth in 1881 surgery has made tremendous progress leading to improved surgical mortality and morbidity. However, while treatment of early gastric cancer is frequently curative, 5-year survival rates for advanced gastric cancer remain dismal despite the application of perioperative multimodal treatment concepts. In this article we will outline key clinical trials that have lead to an improvement in treatment of gastric cancer patients with specific emphasis on the last 20 years. We will then outline recent concepts and key clinical trials that are currently being conducted in the field. Finally we will outline open questions that remain to be elucidated in the future.
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias Gástricas
/
Ensaios Clínicos como Assunto
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article