Epidemiological, virological, and entomological characteristics of dengue from 1978 to 2009 in Guangzhou, China.
J Vector Ecol
; 37(1): 230-40, 2012 Jun.
Article
em En
| MEDLINE
| ID: mdl-22548558
ABSTRACT
To understand its unprecedented resurgence, we examined the epidemiological, virological, and entomological features of dengue in Guangzhou during 1978-2009. Cases reported to the Guangzhou Centre for Disease Control and Prevention and data from virological and entomological surveillance were analyzed from three periods 1978-1988, 1989-1999, and 2000-2009. Although cases decreased over time 6,649 (1978-1988) to 6,479 (1989-1999) to 2,526 (2000-2009), geographical expansion resulted in districts with an average incidence >2.5/100,000, increasing from five (1978-1988, 1989-1999) to seven (2000-2009). Age distribution (mean age 34.9 years) provided a trend of increasing dengue incidence among adults, and there was a significantly higher incidence among men with a sex ratio of 1.151 (P<0.001). Cases occurred from May through November with a peak between August and October, and a long-term trend was characterized by a three to five-year cyclical pattern. The most frequently isolated serotypes were DENV-2 (1978-1988) and DENV-1 (1989-1999 and 2000-2009). Seasonal fluctuations in immature densities of Aedes albopictus (sole transmission vector in Guangzhou) were consistent with the dengue seasonality. After a 30-year apparent absence, DENV-3 had reemerged in 2009. The current epidemiological situation is highly conducive to periodic dengue resurgences. Thus, a high degree of surveillance and strict control measures in source reduction should be maintained.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Dengue
/
Insetos Vetores
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article