Human papillomavirus is associated with breast cancer in the north part of Iran.
ScientificWorldJournal
; 2012: 837191, 2012.
Article
em En
| MEDLINE
| ID: mdl-22566779
ABSTRACT
We have analyzed the possible relevance of HPV infection for breast cancer risk among Iranian women from north part of Iran. Among women with breast cancer, 25.9% had positive test results for HPV DNA in breast tumor samples in contrast to 2.4% of women with noncancer status (P = 0.002). The infection of HPV has increased the risk of breast cancer (OR 14.247; 95% CI 1.558-130.284, P = 0.019). The high-risk HPV genotypes (types 16 and 18) in samples of breast cancer patients were the predominant types (53.34%). Other genotypes detected in breast cancer were HPV-6, HPV-11, HPV-15, HPV-23, and HPV-124, and one isolate could not be genotyped compared to HPV reference sequences. While the sole detected HPV in control specimens was HPV-124. Our study reveals that HPV infection and age are the risk factors in breast cancer development in the north part of Iran.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Mama
/
Infecções por Papillomavirus
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Papillomavirus Humano 16
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Papillomavirus Humano 18
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article