Current immune therapies of autoimmune disease of the nervous system with special emphasis to multiple sclerosis.
Curr Pharm Des
; 18(29): 4513-7, 2012.
Article
em En
| MEDLINE
| ID: mdl-22612753
ABSTRACT
Autoimmune diseases of the nervous system such as myasthenia gravis, inflammatory demyelinating polyneuropathies, multiple sclerosis and others are still not curable. Yet the introduction of modern immune therapies could significantly improve the prospects of many patients affected by these disorders. In addition to steroids and immunosuppression i.v. immunoglobulins are used for treatment of myasthenia gravis and chronic inflammatory demyelinating polyneuropathy. Interferons, glatiramer acetate, natalizumab and fingolimod are applied in multiple sclerosis. The ever-improving efficacy of the drugs has to be balanced against the increasing risk of possible severe adverse effects.
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Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes do Sistema Nervoso
/
Fatores Imunológicos
/
Esclerose Múltipla
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article