Toxicological effect of herbicides (diuron and bentazon) on snake venom and electric eel acetylcholinesterase.
Bull Environ Contam Toxicol
; 89(2): 229-33, 2012 Aug.
Article
em En
| MEDLINE
| ID: mdl-22653306
ABSTRACT
The toxicological effects of the active ingredients of the herbicides diuron and bentazon on the activity of acetylcholinesterase (AChE) of krait (Bungarus sindanus) venom and electric eel (Electrophorus electricus) were studied. The diuron and entazon caused non-competitive inhibition of AChE from both species. For the venom AChE, the calculated IC50 for diuron and bentazon were found to be 3.25 and 0.14 µM, while for eel AChE, the respective IC50 values were 3.6 and 0.135 µM. In comparison, bentazon was a more potent inhibitor than diuron of AChE from both species. The insecticide lindane did not have any inhibitory effect on AChE activity in either species, even when tested at high concentrations (200-800 µM).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Acetilcolinesterase
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Venenos de Serpentes
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Benzotiadiazinas
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Diurona
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Herbicidas
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article