[A case of drug-induced pulmonary injury showing organizing pneumonia pattern due to S-1].
Gan To Kagaku Ryoho
; 39(6): 955-7, 2012 Jun.
Article
em Ja
| MEDLINE
| ID: mdl-22705691
ABSTRACT
Reported here is the case of a 76-year-old male with gastric cancer. Distal gastrectomy was performed after his admission to our hospital. Histopathologically, the cancer was determined to be in the advanced stage. Combination chemotherapy with CDDP and S-1 was administered for 6 courses, after which S-1 was used alone. Chest X-ray and CT showed multiple dispersed lesions in the lung. Further examination by bronchoscope was performed. Histopathological examination of a biopsy specimen revealed the lesion to be organizing pneumonia. A drug-induced lymphocyte stimulation test (DLST) for S-1 proved to be positive. Discontinuation of S-1 administration led to natural improvement of the pneumonia. These results suggest that S-1 had induced the organizing pneumonia.
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Base de dados:
MEDLINE
Assunto principal:
Ácido Oxônico
/
Pneumonia
/
Tegafur
/
Lesão Pulmonar
/
Antimetabólitos Antineoplásicos
Idioma:
Ja
Ano de publicação:
2012
Tipo de documento:
Article