Bronchiolitis associated with exposure to artificial butter flavoring in workers at a cookie factory in Brazil.
J Bras Pneumol
; 38(3): 395-9, 2012.
Article
em En, Pt
| MEDLINE
| ID: mdl-22782611
ABSTRACT
OBJECTIVE:
To report the cases of four patients with bronchiolitis caused by exposure to artificial butter flavoring at a cookie factory in Brazil.METHODS:
We described the clinical, tomographic, and spirometric findings in the four patients, as well as the lung biopsy findings in one of the patients.RESULTS:
All four patients were young male nonsmokers and developed persistent airflow obstruction (reduced FEV1/FVC ratio and FEV1 at 25-44% of predicted) after 1-3 years of exposure to diacetyl, without the use of personal protective equipment, at a cookie factory. The HRCT findings were indicative of bronchiolitis. In one patient, the surgical lung biopsy revealed bronchiolitis obliterans accompanied by giant cells.CONCLUSIONS:
Bronchiolitis resulting from exposure to artificial flavoring agents should be included in the differential diagnosis of airflow obstruction in workers in Brazil.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Manteiga
/
Bronquiolite
/
Indústria Alimentícia
/
Exposição Ocupacional
/
Exposição por Inalação
/
Aromatizantes
/
Doenças Profissionais
Idioma:
En
/
Pt
Ano de publicação:
2012
Tipo de documento:
Article