An evaluation of the ability of leucocyte depletion filters to remove components of amniotic fluid.
Anaesthesia
; 67(10): 1152-7, 2012 Oct.
Article
em En
| MEDLINE
| ID: mdl-22804692
ABSTRACT
Haemorrhage remains an important cause of maternal mortality worldwide. Cell salvage carries a theoretical risk of amniotic fluid embolus syndrome and is too expensive for use in many parts of the world. To explore cheaper options, we investigated whether a leucocyte depletion filter alone removes components of pure amniotic fluid. Amniotic fluid was collected from 10 women during elective caesarean section and passed through a LeukoGuard® RS filter. Pre- and post-filtration samples were compared in the laboratory. Lamellar bodies and fetal squames were almost completely removed (filtration efficacy 96.6% and 99.9%, respectively; p<0.0001 and <0.0004), and hair was completely removed (p=0.002). Filtration had no effect on concentrations of α-fetoprotein, tissue factor or endothelin-1, or on the presence of meconium or vernix. Additional work is required to evaluate whether cell salvage using filtration alone may be useful in maternal haemorrhage in the developing world.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Técnicas Citológicas
/
Recuperação de Sangue Operatório
/
Filtração
/
Líquido Amniótico
/
Leucócitos
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article