Safety and efficacy of splenic artery coil embolization for hypersplenism in liver cirrhosis.
Acta Radiol
; 53(8): 862-7, 2012 Oct 01.
Article
em En
| MEDLINE
| ID: mdl-22855417
ABSTRACT
BACKGROUND:
Partial splenic artery embolization is an effective treatment for hypersplenism but often lacks long-term benefits.PURPOSE:
To evaluate the long-term effects of coil embolization of the splenic artery in patients with liver cirrhosis and hypersplenism. MATERIAL ANDMETHODS:
Forty-nine patients with liver cirrhosis and hypersplenism underwent coil embolization of the main splenic artery. The coils were deployed in the mid- or distal segment of the splenic artery to allow collateral blood flow to the spleen. The following data were collected from 2 weeks to 4 years after the embolization technical success, length of hospital stay, white blood cell count, platelet count, splenic volume, and complication.RESULTS:
The technical success rate of splenic artery coil embolization was 100%. The post embolization syndrome rate was 75% (36/49) with no incidence of major complications. The mean length of hospital stay was 9 days. After embolization, the patient's white blood and platelet counts increased significantly, peaked at 2 weeks, and gradually decreased during the 4-year follow-up period, but remained at significantly higher levels than pre-embolization levels. Follow-up CT scans demonstrated a gradual increase in the volume of the enhanced portions of the spleens with a decrease in the volume of unenhanced portion. No significant changes occurred in the red blood cell count and liver function after the embolization.CONCLUSION:
Embolization of the mid-and distal main splenic artery with coils is a safe and effective treatment of hypersplenism in cirrhosis with long-term hematologic benefits.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Embolização Terapêutica
/
Hiperesplenismo
/
Cirrose Hepática
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article