Carbonyl-twisted 6-acyl-2-dialkylaminonaphthalenes as solvent acidity sensors.
J Org Chem
; 78(5): 1784-9, 2013 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-22894649
ABSTRACT
Derivatives of 2-propionyl-6-dimethylaminonaphthalene (PRODAN) with twisted carbonyl groups were investigated as highly responsive sensors of H-bond donating ability. The PRODAN derivative bearing a pivaloyl group (4) was prepared. The torsion angle between the carbonyl and naphthalene is 26° in the crystal. It shows solvatochromism that is similar to five other PRODAN derivatives (1-3, 5, 6). Twisted-carbonyl derivatives 3, 4, and 6 show strong fluorescence quenching in protic solvents. The order of magnitude of the quenching is linearly related to the H-bond donating ability of the solvent (SA) but not to other solvent properties. Binary mixtures of protic solvents show specific interaction effects with respect to quenching and solvatochromism. Aggregation in water is an issue with the pivaloyl derivatives.
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MEDLINE
Assunto principal:
Solventes
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Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article