Evaluation of immunostimulatory activities of synthetic mannose-containing structures mimicking the ß-(1->2)-linked cell wall mannans of Candida albicans.
Clin Vaccine Immunol
; 19(11): 1889-93, 2012 Nov.
Article
em En
| MEDLINE
| ID: mdl-22993407
ABSTRACT
Immunostimulatory properties of synthetic structures mimicking the ß-(1â2)-linked mannans of Candida albicans were evaluated in vitro. Contrary to earlier observations, tumor necrosis factor (TNF) production was not detected after stimulation with mannotetraose in mouse macrophages. Divalent disaccharide 1,4-bis(α-D-mannopyranosyloxy)butane induced TNF and some molecules induced low levels of gamma interferon (IFN-γ) in human peripheral blood mononuclear cells (PBMC).
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Candida albicans
/
Mananas
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article