Is US-guided core needle biopsy (CNB) enough in probably benign nodules with interval growth?
Ultraschall Med
; 33(7): E145-E150, 2012 Dec.
Article
em En
| MEDLINE
| ID: mdl-23023453
ABSTRACT
PURPOSE:
To investigate whether ultrasound-guided 14-gauge core needle biopsy (US-CNB) is efficient in the diagnosis of probably benign lesions showing interval growth on follow-up US.â MATERIALS ANDMETHODS:
From March 2008 to August 2009, 116 breast lesions in 113 women (mean age 41.2 years, range 19â-â63 years) which were initially assessed as category 3 showing interval growth on follow-up US underwent US-CNB, and subsequent US-guided vacuum-assisted excision, surgical excision or follow-up US for at least 12 months. Diagnostic performances of US-CNB were evaluated with histopathologic results and follow-up US as standard reference. Clinical features of the patient and lesions characteristics including follow-up interval (I), the most increased diameter (D), D per I, increased volume (%V) and %V per I were calculated and compared.RESULTS:
Of the 116 lesions, 4 lesions were diagnosed as malignancy and 112 as benign on final pathology. Malignancy rate of probably benign lesions showing interval growth was 3.4â% (4/116). Incorrect biopsy rate was 0.9â% (1/116). Palpability or newly developed suspicious US features were more associated with malignancy, 75.0 to 13.4â% and 50.0 to 25.9â%, respectively, but without significance (pâ=â0.063 and 0.290). Significant differences were seen in average rank when comparing between benign and malignancy in D, %V, D per follow-up interval (I), and %V/I (pâ=â0.037, 0.017, 0.043 and 0.009, respectively).CONCLUSION:
US-CNB is an efficient diagnostic method for probably benign lesions showing interval growth, with discordant biopsy rate of 0.9â%.
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Base de dados:
MEDLINE
Assunto principal:
Biópsia por Agulha
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Neoplasias da Mama
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Ultrassonografia Mamária
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Ultrassonografia de Intervenção
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Doença da Mama Fibrocística
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article