Heterologous production of 4-O-demethylbarbamide, a marine cyanobacterial natural product.
Org Lett
; 14(23): 5824-7, 2012 Dec 07.
Article
em En
| MEDLINE
| ID: mdl-23148802
ABSTRACT
Heterologous expression of the barbamide biosynthetic gene cluster, obtained from the marine cyanobacterium Moorea producens, in the terrestrial actinobacterium Streptomyces venezuelae, resulted in the production of a new barbamide congener 4-O-demethylbarbamide, demonstrating the potential of this approach for investigating the assembly and tailoring of complex marine natural products.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Tiazóis
/
Produtos Biológicos
/
Cianobactérias
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article