Grape seed extract as a potential remineralizing agent: a comparative in vitro study.
J Contemp Dent Pract
; 13(4): 425-30, 2012 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-23151686
ABSTRACT
OBJECTIVE:
Remineralization is an effective treatment that may stop or reverse early tooth decay. Grape seed extract (GSE) is the potential remineralizing agent under investigation. MATERIALS ANDMETHODS:
Sound human tooth sections were obtained from the cervical portion of the root and stored in demineralizing solution at 37°C for 96 hours to induce artificial root caries lesions. The sections were divided into four treatment groups including 6.5% grape seed extract, sodium monofluorophosphate (220 ppm) with 0.05% calcium glycerophosphate, 0.5% calcium glycerophosphate and control (no treatment). An in vitro pH cycling model was used to cycle the demineralized specimens through treatment solutions, acidic buffer and neutral buffer for 8 days at 6 cycles per day. Subsequently, they were evaluated using confocal laser scanning microscope. Data were analyzed using analysis of variance (p < 0.05).RESULTS:
GSE revealed less demineralization and more remineralization compared with other groups.CONCLUSION:
GSE promotes remineralization of artificial root caries lesions. CLINICALSIGNIFICANCE:
The search for the perfect remineralizing agent continues to this day. GSE could be a welcome addition to the remineralization armamentarium.
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Base de dados:
MEDLINE
Assunto principal:
Remineralização Dentária
/
Cárie Radicular
/
Proantocianidinas
/
Extrato de Sementes de Uva
/
Antioxidantes
Idioma:
En
Ano de publicação:
2012
Tipo de documento:
Article