A novel green gelatin-agar microencapsulation system with P. urinaria as an improved anti-A. niger model.
Carbohydr Polym
; 92(1): 877-80, 2013 Jan 30.
Article
em En
| MEDLINE
| ID: mdl-23218379
In this study, a novel green microencapsulation system was used to develop Phyllanthus urinaria (PU) extract containing microcapsules. Agar was used with gelatin as the wall matrix materials of microcapsules to prevent the use of toxic crosslinker formaldehyde. Microencapsulated PU extract was developed to improve the potential antifungal activities of PU water extracts. The active components and surface morphology of PU extract containing microcapsules were analyzed by liquid chromatography/mass spectrometry and scanning electron microscopy, respectively. The in vitro release study demonstrated that approximately 80% of drug was released after 120 h. PU loaded microcapsules were shown to have a stronger anti-Aspergillus niger activity than the free drug.
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Base de dados:
MEDLINE
Assunto principal:
Aspergillus niger
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Extratos Vegetais
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Phyllanthus
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Composição de Medicamentos
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article