Possible link of pioglitazone with bladder cancer in Japanese patients with type 2 diabetes.
Diabetes Res Clin Pract
; 99(2): e21-3, 2013 Feb.
Article
em En
| MEDLINE
| ID: mdl-23228390
ABSTRACT
We retrospectively examined the frequency of bladder cancer in Japanese patients with type 2 diabetes in relation to use of pioglitazone. Among a total of 663 patients identified to be taking pioglitazone, 9 had bladder cancer (1.36%). Overall the hazard ratio of 1.75 [95% CI 0.89-3.45] for pioglitazone for bladder cancer was not significant. However the prevalence of bladder cancer was 2.10% in patients taking pioglitazone for less than 24 months which was significant increased (HR 2.73 [95% CI 1.11-6.72]).
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Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Bexiga Urinária
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Tiazolidinedionas
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Diabetes Mellitus Tipo 2
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Hipoglicemiantes
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article