A versatile and practical method for regioselective synthesis of polysubstituted furanonaphthoquinones.
Org Biomol Chem
; 11(5): 828-34, 2013 Feb 07.
Article
em En
| MEDLINE
| ID: mdl-23235915
ABSTRACT
An efficient and attractive synthesis of a series of novel poly-functionalized phosphorus zwitterions was achieved via three-component reactions of the corresponding functional nucleophiles, aldehydes, and Bu(3)P in the presence of acidic promoter. These polysubstituted zwitterions could regioselectively undergo further transformations to synthetically important furanonaphthoquinones and related products via the intramolecular Wittig reaction. These methods could have potential application in synthetic and pharmaceutical chemistry for its facilitation and easily accessible commercial materials.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Naftoquinonas
/
Furanos
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article