Targeting cancer stem cells via dendritic-cell vaccination.
Oncoimmunology
; 1(8): 1401-1403, 2012 Nov 01.
Article
em En
| MEDLINE
| ID: mdl-23243607
ABSTRACT
Using syngeneic murine tumor models established in immunocompetent hosts, we showed that cancer stem cells are immunogenic and can be selectively targeted by dendritic cell-based vaccines. This new approach induced both humoral and cellular immune responses and conferred significantly superior antitumor immunity as compared with conventional vaccines.
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MEDLINE
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En
Ano de publicação:
2012
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Article