Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches.

Bhattacharya, Sudin; Shoda, Lisl K M; Zhang, Qiang; Woods, Courtney G; Howell, Brett A; Siler, Scott Q; Woodhead, Jeffrey L; Yang, Yuching; McMullen, Patrick; Watkins, Paul B; Andersen, Melvin E.

Afiliação

Bhattacharya S; Institute for Chemical Safety Sciences, The Hamner Institutes for Health Sciences Research Triangle Park, NC, USA.

Front Physiol ; 3: 462, 2012.

Article em En | MEDLINE | ID: mdl-23248599

Palavras-chave

chemical toxicity; computational toxicology; drug toxicity; multi-scale modeling; systems toxicology; toxicity pathways; virtual liver

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2012 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2012 Tipo de documento: Article