Long-term red blood cell exchange in children with sickle cell disease: manual or automatic?
Transfus Apher Sci
; 48(2): 219-22, 2013 Apr.
Article
em En
| MEDLINE
| ID: mdl-23257506
ABSTRACT
Little information is available on erythrocytapheresis in children with sickle cell disease, and no comparison has ever been made with manual exchanges in a long-term blood exchange program. We matched a historical cohort of five patients who received 60 erythrocytapheresis procedures with five who received 124 manual exchanges. Long-term erythrocytapheresis was feasible and well-tolerated even in children of low weight. In a long-term approach, automated exchanges were more efficient in maintaining a low HbS level, and exchanges could be spaced out. This approach appears especially useful in the cases where the HbS level must be maintained below 30%.
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1
Base de dados:
MEDLINE
Assunto principal:
Transfusão de Eritrócitos
/
Anemia Falciforme
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article