Modeling obesity and its associated disorders in Drosophila.
Physiology (Bethesda)
; 28(2): 117-24, 2013 Mar.
Article
em En
| MEDLINE
| ID: mdl-23455770
ABSTRACT
In recent years, obesity has been recognized as a major public health problem due to its increased prevalence in both children and adults and its association with numerous life-threatening complications including diabetes, heart disease, hypertension, and cancer. Obesity is a complex disorder that is the result of the interaction between predisposing genetic and environmental factors. However, the precise nature of these gene-gene and gene-environment interactions remains unclear. Here, we will describe recent studies demonstrating how fruit flies can be used to identify and characterize the mechanisms underlying obesity and to establish models of obesity-associated disorders.
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Base de dados:
MEDLINE
Assunto principal:
Drosophila
/
Obesidade
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article