[Measurement of acetonitrile in blood and urine by head-space gas chromatography].
Fa Yi Xue Za Zhi
; 28(6): 422-5, 2012 Dec.
Article
em Zh
| MEDLINE
| ID: mdl-23484321
ABSTRACT
OBJECTIVE:
To establish the method for measurement of acetonitrile in blood and urine by head-space gas chromatography.METHODS:
DB-ALC1 (30 m x 320 microm x 1.8 microm) and DB-ALC2 (30 m x 320 microm x 1.2 microm) capillary column were used to measure the acetonitrile in blood and urine with the isopropanol as internal standard reference.RESULTS:
The limits of detection of acetonitrile in both blood and urine were 0.5 microg/mL, with a linear range of 5-1000 microg/mL (r = 0.999).The accuracy of this method was 93.2%-98.0%. The RSD for the intra-day and inter-day were less than 3.7%.CONCLUSION:
The method is capable for measurement analysis of acetonitrile in blood and urine.
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Base de dados:
MEDLINE
Assunto principal:
Acetonitrilas
/
Cromatografia Gasosa
Idioma:
Zh
Ano de publicação:
2012
Tipo de documento:
Article