Rhodium(III)-catalyzed direct selective C(5)-H oxidative annulations of 2-substituted imidazoles and alkynes by double C-H activation.
Org Lett
; 15(8): 1878-81, 2013 Apr 19.
Article
em En
| MEDLINE
| ID: mdl-23537406
Double C-H activations of C(5)-H and Csp(2)-H of 2-substituted N-vinyl- or arylimidazoles were realized without heteroatom-directing assistance by rhodium(III) catalyst. A subsequent oxidative annulation reaction with alkynes efficiently produced aza-fused heterocycles with high molecular complexity in low to excellent yields.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Ródio
/
Alcinos
/
Compostos Heterocíclicos
/
Imidazóis
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article