Synthesis of functionalised 4H-quinolizin-4-ones via tandem Horner-Wadsworth-Emmons olefination/cyclisation.
Org Biomol Chem
; 11(20): 3337-40, 2013 May 28.
Article
em En
| MEDLINE
| ID: mdl-23558690
ABSTRACT
4H-Quinolizin-4-ones are a unique class of heterocycle with valuable physicochemical properties and which are emerging as key pharmacophores for a range of biological targets. A tandem Horner-Wadsworth-Emmons olefination/cyclisation method has been developed to allow facile access to substituted 4H-quinolizin-4-ones encoded with a range of functional groups.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Quinolizinas
/
Alcenos
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article