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Development of a chemical probe for identifying protein targets of α-oxoaldehydes.
Sibbersen, Christian; Palmfeldt, Johan; Hansen, Jakob; Gregersen, Niels; Jørgensen, Karl Anker; Johannsen, Mogens.
Afiliação
  • Sibbersen C; Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark.
Chem Commun (Camb) ; 49(38): 4012-4, 2013 May 11.
Article em En | MEDLINE | ID: mdl-23563755
ABSTRACT
The development of a chemical probe for identifying the protein targets of reactive electrophilic α-oxoaldehydes such as methylglyoxal is presented. The probe is evaluated against methylglyoxal using human serum albumin as well as using living cells and lysates.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aldeído Pirúvico / Albumina Sérica / Alcinos / Corantes Fluorescentes Idioma: En Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aldeído Pirúvico / Albumina Sérica / Alcinos / Corantes Fluorescentes Idioma: En Ano de publicação: 2013 Tipo de documento: Article