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Metabolomics reveals trichloroacetate as a major contributor to trichloroethylene-induced metabolic alterations in mouse urine and serum.
Fang, Zhong-Ze; Krausz, Kristopher W; Tanaka, Naoki; Li, Fei; Qu, Aijuan; Idle, Jeffrey R; Gonzalez, Frank J.
Afiliação
  • Fang ZZ; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD, 20892, USA.
  • Krausz KW; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD, 20892, USA.
  • Tanaka N; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD, 20892, USA.
  • Li F; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD, 20892, USA.
  • Qu A; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD, 20892, USA.
  • Idle JR; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD, 20892, USA.
  • Gonzalez FJ; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 37, Room 3106, Bethesda, MD, 20892, USA. gonzalef@mail.nih.gov.
Arch Toxicol ; 87(11): 1975-1987, 2013 Nov.
Article em En | MEDLINE | ID: mdl-23575800
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Tricloroacético / Tricloroetileno / Metabolômica / Doença Hepática Induzida por Substâncias e Drogas / Metabolismo Idioma: En Ano de publicação: 2013 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ácido Tricloroacético / Tricloroetileno / Metabolômica / Doença Hepática Induzida por Substâncias e Drogas / Metabolismo Idioma: En Ano de publicação: 2013 Tipo de documento: Article