[Macroglobulin family proteins in breast cancer].

ABSTRACT

Determined serum levels of alpha-2-macroglobulin (a2-MG) and pregnancy-associate alpha-2-glycoprotein (a2-PAG) in 98 breast cancer patients stage I-IV prior to the special antitumor treatment. Statistically significant negative correlative dependence of the a2-PAG in the blood and lifetime of patients is proved. We believe that the definition of pre-treatment level of a serum a2-MG and a2-PAG concentrations for patients with breast cancer, can be used as an additional predictor of life expectancy.