Three new ursane-type triterpenes from the leaves of Rehmannia glutinosa.
Fitoterapia
; 89: 15-9, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-23707195
ABSTRACT
Three new ursane-type triterpenes, glutinosalactone A-C (1-3), were isolated from the 50% aqueous acetone extract of the leaves of Rehmannia glutinosa. Their structures were elucidated on the basis of spectral analysis (IR, NMR and MS spectroscopy). The cytotoxic effects of compounds 1-3 against three human cancer cell lines (MCF-7, MG63 and HepG2) were also evaluated. Compound 3 showed cytotoxic activities with IC50 values of 8.35-39.25 µM.
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Base de dados:
MEDLINE
Assunto principal:
Triterpenos
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Folhas de Planta
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Rehmannia
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Neoplasias
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Antineoplásicos Fitogênicos
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article