Chemoselective benzylation of unprotected anthranilic acids with benzhydryl alcohols by water-soluble Au(III)/TPPMS in water.
J Org Chem
; 78(13): 6714-20, 2013 Jul 05.
Article
em En
| MEDLINE
| ID: mdl-23745757
ABSTRACT
A novel and efficient method for the benzylation of unprotected anthranilic acids with benzhydryl alcohols using water-soluble Au(III)/TPPMS in water is developed. Water plays an important role in our catalytic system. This new protocol could be used for not only N-benzylation, but also chemoselective C-benzylation by the Friedel-Crafts reaction.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fosfinas
/
Benzenossulfonatos
/
Compostos Benzidrílicos
/
Álcoois
/
Ortoaminobenzoatos
/
Ouro
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article