Is there a rationale for an anesthesiologist's role against cancer recurrence?
Acta Anaesthesiol Belg
; 64(1): 15-24, 2013.
Article
em En
| MEDLINE
| ID: mdl-23767173
ABSTRACT
Growth of tumors can accelerate during the peri-operative period. Accordingly, early relapse of cancer occurs in some patients during the first two postoperative years. Temporal and biologic analyses of cancer pathophysiology suggest a link between peri-operative pathophysiological changes and acceleration of tumor growth. Understanding the role of inflammation and its consequences (i.e., immune response, growth factors, dissemination of tumor cells) could lead to define a role of anesthesiologists in reducing cancer recurrence following surgery. We argue for peri-operative pharmacological interventions to reduce cancer relapse, with a focus on non-steroidal anti-inflammatory drugs.
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Base de dados:
MEDLINE
Assunto principal:
Papel do Médico
/
Anti-Inflamatórios não Esteroides
/
Inflamação
/
Anestesiologia
/
Neoplasias
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article