Short-term associations between fine and coarse particulate matter and hospitalizations in Southern Europe: results from the MED-PARTICLES project.
Environ Health Perspect
; 121(9): 1026-33, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-23777832
ABSTRACT
BACKGROUND:
Evidence on the short-term effects of fine and coarse particles on morbidity in Europe is scarce and inconsistent.OBJECTIVES:
We aimed to estimate the association between daily concentrations of fine and coarse particles with hospitalizations for cardiovascular and respiratory conditions in eight Southern European cities, within the MED-PARTICLES project.METHODS:
City-specific Poisson models were fitted to estimate associations of daily concentrations of particulate matter with aerodynamic diameter ≤ 2.5 µm (PM2.5), ≤ 10 µm (PM10), and their difference (PM2.5-10) with daily counts of emergency hospitalizations for cardiovascular and respiratory diseases. We derived pooled estimates from random-effects meta-analysis and evaluated the robustness of results to co-pollutant exposure adjustment and model specification. Pooled concentration-response curves were estimated using a meta-smoothing approach.RESULTS:
We found significant associations between all PM fractions and cardiovascular admissions. Increases of 10 µg/m3 in PM2.5, 6.3 µg/m3 in PM2.5-10, and 14.4 µg/m3 in PM10 (lag 0-1 days) were associated with increases in cardiovascular admissions of 0.51% (95% CI 0.12, 0.90%), 0.46% (95% CI 0.10, 0.82%), and 0.53% (95% CI 0.06, 1.00%), respectively. Stronger associations were estimated for respiratory hospitalizations, ranging from 1.15% (95% CI 0.21, 2.11%) for PM10 to 1.36% (95% CI 0.23, 2.49) for PM2.5 (lag 0-5 days).CONCLUSIONS:
PM2.5 and PM2.5-10 were positively associated with cardiovascular and respiratory admissions in eight Mediterranean cities. Information on the short-term effects of different PM fractions on morbidity in Southern Europe will be useful to inform European policies on air quality standards.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Doenças Respiratórias
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Doenças Cardiovasculares
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Cidades
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Material Particulado
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Hospitalização
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article