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The inclusion complex of 4-hydroxynonenal with a polymeric derivative of ß-cyclodextrin enhances the antitumoral efficacy of the aldehyde in several tumor cell lines and in a three-dimensional human melanoma model.
Pizzimenti, Stefania; Ciamporcero, Eric; Pettazzoni, Piergiorgio; Osella-Abate, Simona; Novelli, Mauro; Toaldo, Cristina; Husse, Miriam; Daga, Martina; Minelli, Rosalba; Bisazza, Agnese; Ferruti, Paolo; Ranucci, Elisabetta; Grazia Bernengo, Maria; Dianzani, Chiara; Biasi, Fiorella; Cavalli, Roberta; Barrera, Giuseppina.
Afiliação
  • Pizzimenti S; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy. Electronic address: stefania.pizzimenti@unito.it.
  • Ciamporcero E; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy.
  • Pettazzoni P; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy.
  • Osella-Abate S; Section of Dermatology, Department of Medical Sciences, University of Turin, 10125 Turin, Italy.
  • Novelli M; Section of Dermatology, Department of Medical Sciences, University of Turin, 10125 Turin, Italy.
  • Toaldo C; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy.
  • Husse M; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy.
  • Daga M; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy.
  • Minelli R; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy.
  • Bisazza A; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy.
  • Ferruti P; Department of Chemistry, University of Milan, Milano, Italy.
  • Ranucci E; Department of Chemistry, University of Milan, Milano, Italy.
  • Grazia Bernengo M; Section of Dermatology, Department of Medical Sciences, University of Turin, 10125 Turin, Italy.
  • Dianzani C; Department of Drug Science and Technology, University of Turin, 10125 Turin, Italy.
  • Biasi F; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy.
  • Cavalli R; Section of Dermatology, Department of Medical Sciences, University of Turin, 10125 Turin, Italy.
  • Barrera G; Department of Clinical and Biological Sciences, University of Turin, 10125 Turin, Italy.
Free Radic Biol Med ; 65: 765-777, 2013 Dec.
Article em En | MEDLINE | ID: mdl-23811007
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Ciclodextrinas / Aldeídos / Melanoma / Antineoplásicos Idioma: En Ano de publicação: 2013 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Beta-Ciclodextrinas / Aldeídos / Melanoma / Antineoplásicos Idioma: En Ano de publicação: 2013 Tipo de documento: Article