Severe and morbid obesity in Crohn's disease patients: prevalence and disease associations.
Digestion
; 88(1): 26-32, 2013.
Article
em En
| MEDLINE
| ID: mdl-23816835
ABSTRACT
BACKGROUND:
Crohn's disease (CD) is frequently associated with weight loss and malnutrition. However, as the prevalence of obesity increases worldwide, it may become a clinical problem even in CD.AIM:
To assess the prevalence of severe/morbid obesity in CD patients and to compare their disease characteristics to nonobese CD patients.METHODS:
A retrospective analysis of a computerized CD patient database was performed to identify severely/morbidly obese patients (BMI >35). Prevalence was compared to data of the general population. Severely/morbidly obese CD patients were then compared to randomly selected nonobese CD patients (BMI <30) in a 13 ratio.RESULTS:
Thirteen severely/morbidly obese patients out of 560 CD patients were found (2.3%), which is significantly lower than the prevalence in the general population (5.6%, p = 0.001). When compared to 39 nonobese CD patients, colonic disease was significantly more common among severely/morbidly obese CD patients (odds ratio 6, 95% CI 1.35-26.3, p = 0.02), while there was no difference in other disease parameters. Interestingly, 4 morbidly obese CD patients had undergone laparoscopic sleeve gastrectomy for treatment of morbid obesity with a favorable surgical course.CONCLUSION:
CD in severely/morbidly obese patients is more often colonic, but otherwise no different than CD in nonobese patients. Sleeve gastrectomy is a viable therapeutic option for morbidly obese CD patients.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Obesidade Mórbida
/
Doença de Crohn
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article