Faecalibacterium prausnitzii and human intestinal health.
Curr Opin Microbiol
; 16(3): 255-61, 2013 Jun.
Article
em En
| MEDLINE
| ID: mdl-23831042
ABSTRACT
Faecalibacterium prausnitzii is the most abundant bacterium in the human intestinal microbiota of healthy adults, representing more than 5% of the total bacterial population. Over the past five years, an increasing number of studies have clearly described the importance of this highly metabolically active commensal bacterium as a component of the healthy human microbiota. Changes in the abundance of F. prausnitzii have been linked to dysbiosis in several human disorders. Administration of F. prausnitzii strain A2-165 and its culture supernatant have been shown to protect against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in mice. Here, we discuss the role of F. prausnitzii in balancing immunity in the intestine and the mechanisms involved.
Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Simbiose
/
Trato Gastrointestinal
/
Bactérias Gram-Positivas
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article