Best practices for veterinary toxicologic clinical pathology, with emphasis on the pharmaceutical and biotechnology industries.
Vet Clin Pathol
; 42(3): 252-69, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-23889060
ABSTRACT
The purpose of this paper by the Regulatory Affairs Committee (RAC) of the American Society for Veterinary Clinical Pathology (ASVCP) is to review the current regulatory guidances (eg, guidelines) and published recommendations for best practices in veterinary toxicologic clinical pathology, particularly in the pharmaceutical and biotechnology industries, and to utilize the combined experience of ASVCP RAC to provide updated recommendations. Discussion points include (1) instrumentation, validation, and sample collection, (2) routine laboratory variables, (3) cytologic laboratory variables, (4) data interpretation and reporting (including peer review, reference intervals and statistics), and (5) roles and responsibilities of clinical pathologists and laboratory personnel. Revision and improvement of current practices should be in alignment with evolving regulatory guidance documents, new technology, and expanding understanding and utility of clinical pathology. These recommendations provide a contemporary guide for the refinement of veterinary toxicologic clinical pathology best practices.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Patologia Clínica
/
Patologia Veterinária
/
Biotecnologia
/
Pessoal de Laboratório Médico
/
Indústria Farmacêutica
/
Laboratórios
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article