Okra polysaccharide improves metabolic disorders in high-fat diet-induced obese C57BL/6 mice.
Mol Nutr Food Res
; 57(11): 2075-8, 2013 Nov.
Article
em En
| MEDLINE
| ID: mdl-23894043
ABSTRACT
Okra is a tropical vegetable that is rich in polysaccharides. Here, we investigated the effects of okra polysaccharide (OP) on metabolic disorders in mice. We found that OP lowered body weight and glucose levels, improved glucose tolerance, and decreased serum total cholesterol levels in high-fat diet-fed C57BL/6 mice. OP regulated the gene expression of liver X receptors (LXRs) and peroxisome proliferator-activated receptors (PPARs) and their target genes in the liver and the adipose tissue of the mice. These results suggest that OP may have therapeutic effects on metabolic diseases via the inhibition of LXR and PPAR signaling.
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MEDLINE
Assunto principal:
Polissacarídeos
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Extratos Vegetais
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Abelmoschus
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Dieta Hiperlipídica
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Doenças Metabólicas
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article