IL-4 and IL-13 mediated down-regulation of CD8 expression levels can dampen anti-viral CD8⺠T cell avidity following HIV-1 recombinant pox viral vaccination.
Vaccine
; 31(41): 4548-55, 2013 Sep 23.
Article
em En
| MEDLINE
| ID: mdl-23933364
Palavras-chave
ANOVA; BD; Beckton Dickinson; CD8 expression; CD8(+) T cell avidity/polyfunctionality; FCS; FPV-HIV; FPV-HIV or VV-HIV encoding murine soluble IL-13Rα2; HIV-1 vaccines/vaccination; ICS; IFN; IFN-I; IL; IL-13 inhibitor vaccines; IL-13 receptor α 2; IL-13Rα2; IL-4/IL-13; LCMV; MFI; Mucosal vaccination; PBS; RBC; SEM; STAT6; T cell receptor; TCR; TNF; VV-HIV; VV-WR; WT; analysis of variance; fetal calf serum; fowlpox virus encoding HIV-1 antigens; i.m.; i.n.; i.p.; interferon; interleukin; intracellular cytokine stain; intramuscular; intranasal; intraperitoneal; lymphocytic choriomeningitis virus; mean fluorescent intensity; pMHC-I; peptide-major histocompatibility class I complexes; phosphate buffer saline; red blood cell; signal transducer and activator of transcription 6; standard error of the mean; tumor necrosis factor; type I interferons; vaccinia virus Western Reserve strain; vaccinia virus encoding HIV-1 antigens; wild-type
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
HIV-1
/
Interleucina-4
/
Antígenos CD8
/
Vacinas contra a AIDS
/
Interleucina-13
/
Linfócitos T CD8-Positivos
Idioma:
En
Ano de publicação:
2013
Tipo de documento:
Article