Keratin 9 is required for the structural integrity and terminal differentiation of the palmoplantar epidermis.

Fu, Dun Jack; Thomson, Calum; Lunny, Declan P; Dopping-Hepenstal, Patricia J; McGrath, John A; Smith, Frances J D; Irwin McLean, W H; Leslie Pedrioli, Deena M

Fu, Dun Jack; Thomson, Calum; Lunny, Declan P; Dopping-Hepenstal, Patricia J; McGrath, John A; Smith, Frances J D; Irwin McLean, W H; Leslie Pedrioli, Deena M.

Afiliação

Fu DJ; Division of Molecular Medicine and Centre for Dermatology and Genetic Medicine, Colleges of Life Sciences and Medicine, Dentistry and Nursing, University of Dundee, Dundee, UK.
Thomson C; Microscopy Facility, College of Life Sciences, University of Dundee, Dundee, UK.
Lunny DP; Epithelial Biology Group, Institute of Medical Biology, Immunos, Singapore.
Dopping-Hepenstal PJ; Guy's and St Thomas' (GSTS) Pathology, St Thomas' Hospital, London, UK.
McGrath JA; St John's Institute of Dermatology, King's College London, London, UK.
Smith FJD; Division of Molecular Medicine and Centre for Dermatology and Genetic Medicine, Colleges of Life Sciences and Medicine, Dentistry and Nursing, University of Dundee, Dundee, UK.
Irwin McLean WH; Division of Molecular Medicine and Centre for Dermatology and Genetic Medicine, Colleges of Life Sciences and Medicine, Dentistry and Nursing, University of Dundee, Dundee, UK.
Leslie Pedrioli DM; Division of Molecular Medicine and Centre for Dermatology and Genetic Medicine, Colleges of Life Sciences and Medicine, Dentistry and Nursing, University of Dundee, Dundee, UK. Electronic address: d.lesliepedrioli@dundee.ac.uk.

J Invest Dermatol ; 134(3): 754-763, 2014 Mar.

Article em En | MEDLINE | ID: mdl-23962810

Assuntos

Epiderme/fisiologia; Queratina-9/genética; Queratina-9/fisiologia; Ceratodermia Palmar e Plantar Epidermolítica/genética; Fatores Etários; Animais; Diferenciação Celular/fisiologia; Proliferação de Células; Citoesqueleto/patologia; Modelos Animais de Doenças; Epiderme/patologia; Hiperpigmentação/genética; Hiperpigmentação/patologia; Ceratodermia Palmar e Plantar Epidermolítica/patologia; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; Fenótipo; RNA Interferente Pequeno/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Epiderme / Ceratodermia Palmar e Plantar Epidermolítica / Queratina-9 Idioma: En Ano de publicação: 2014 Tipo de documento: Article

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